RTCTox Research & Technology Center in Toxicology

Pill Identification

Last update: January 4, 2010

John Lehmann Ph.D.
	Pharmacologist, Neuropharmacologist, Neurotoxicology, Neurotoxicity, Neuropharmacology Consultant
Toxicology Consultant / Neurotoxicology / Pharmacology Expert Witness
	Adverse Drug Reactions Epidemiological, adverse reaction, pharmacoeconomics, outcome research; SAS analysis of health insurance company patient data Drug-Induced Injury - Depo-Medrol (Methylprednisolone), Reglan (Metoclopramide) Opioid / Opiate Overdose - Morphine, Hydrocodone, etc. Statins Toxicity of pharmaceuticals in Neurosurgical procedures
Areas of Toxicology Expertise:
	Causation of Brain and Spine Injury and Death, Respiratory Depression, Drug-Induced Memory Impairment Neurotoxicity, Biochemistry and Neurochemistry of Stroke, Traumatic Brain Injury, Hypoxia-induced Brain Damage, Neuro Toxicology, Neuropharmacology Consultant Design and Conduct of Clinical Trials, Label Development Adequacy of Warning to Physician Learned Intermediary in Medical Malpractice Issues Analysis of NDA, IND, PSUR, label revisions, Investigators' Brochure, other FDA documentation Antiepileptics, Antidepressants Due Diligence by Liability Insurance Carriers of Pharmaceutical Corporations Investment Analysis of Pharmaceutical Corporations - Product Liability Risk Exposure Managed Care Patient Registry Statistical Analysis (Pharmetrics Database, IMS Health Data) SAS Statistical Epidemiology
Description:
	10 years experience as Research Pharmacologist in Pharmaceutical Industry in Drug Discovery in the United States & France; 10 years Faculty in Medical School, Departments of Psychiatry and Neurosurgery, PI of Clinical Trials; Independent Toxicology Consultant / Neuropharmacology Consultant / Pharmacology Consultant for 4 years. 20 years experience in Neurotoxicology / Neurotoxicity Research; Published over 60 peer-reviewed papers.
Contact information
	John Lehmann Ph.D. Pharmikos Inc Homepage:http://rtctox.com/lehmann.htm Website: http://pharmikos.com
Professional Society Membership:
	Member Society of Toxicology (Sot)

Publications:
	86 peer-reviewed papers and chapters available upon request.
	Lehmann J, Arbilla S, Langer SZ. Dopamine receptor mediated inhibition by Pergolide [Permax] of electrically-evoked 3H-dopamine release from striatal slices of cat and rat: slight effect of ascorbate. Naunyn Schmiedebergs Arch Pharmacol. 1981 Aug;317(1):31-5
	Lehmann J, Langer SZ. Muscarinic receptors on dopamine terminals in the cat caudate nucleus: neuromodulation of [3H]dopamine release in vitro by endogenous acetylcholine. Brain Res. 1982 Sep 23;248(1):61-9.


Dictionary of Abbreviations and Acronyms used
Fda	Food and Drug Administration Fda Toxicology Consultant
Ind	Investigational New Drug
NDA	New Drug Application
Ntd	NeuroToxicology Division
Pi	Principal Investigator
Psur	Periodic Safety Update and Review
Sot	Society of Toxicology Expert Witness
Sas	Statistical Analysis Software

Pharmacologist, Neuropharmacologist, Neurotoxicology, Neurotoxicity, Neuropharmacology Consultant

SAS Statistical Epidemiology

Member Society of Toxicology (Sot)

Pharmikos